Cloning and expression of cDNA for rat O6-methylguanine-DNA methyltransferse

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Regulation of O6-Methylguanine-DNA Methyltransferase Levels in Rat Liver and Kidney1

It was found that rat kidney contains a protein similar to that previously described in rat liver which catalyzes the transfer of the methyl group from O6-methylguanine in DNA to a proteinbound cysteine residue. The amount of the renal O6-methylguanine-DNA methyltransferase was increased up to 2.5-fold during renal hypertrophy in response to unilateral nephrectomy or treatment with folie acid. ...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 1991

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/19.20.5597